Modern medicine frequently accomplishes incredible things. From finding new ways to treat “old” conditions to addressing emerging challenges head-on, the field is constantly being pushed forward in new, exciting ways. Undoubtedly, one of the best examples of this is the advent of gene therapy. Gene therapy today is comprised of a variety of methods and treatments, though the basic principle is the same. While gene therapy can be life-altering for those who receive it, it can be equally as momentous for employers and plan sponsors faced with a colossal claim they may not be prepared for. A gene therapy claim can be both extremely costly and entirely unexpected—a combination that could be disastrous.